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EvokeDx icVEP + ERG is a revolutionary technology platform for simplified and objective assessment of the visual pathway.
Developed by Konan Medical and the leading scientists in electro-physiology, EvokeDx delivers many significant enhancements that are simply not available with other VEP devices.
Innovative Design and User Experience
Konan strives to deliver innovative design of both form and function. A space saving, all-in-one form factor delivers true plug-and-play functionality right out of the box, while an intuitive, touch-screen user-experience eliminates the need for costly onsite consultants. You'll be up and running in minutes not days.
Linearized OLED Monitor
Conventional off-the-shelf LCD monitors used by other VEP/ERG manufacturers introduce an undesirable luminance artifact that contaminates the response.
EvokeDx utilizes a cutting-edge, linearized Organic Light Emitting Diode (OLED) monitor which eliminates the luminance artifact, avoiding an unwanted skewed response. Additional benefits include microsecond timing (10x faster than standard LCDs) providing an additional measure of precision.
Patented icVEP
Konan's patented Isolated Check VEP (icVEPTM) is a steady state, low contrast stimulus pattern that is thought to specifically target the magnocellular on pathway.
The icVEP stimulus is presented as multiple, short runs (instead of a single, long run), enabling more reliable data collection while making the test easier on the patient.
Clinical Evidence - Studies
SBIR Glaucoma investigation, Phase I (Columbia) and Phase II (Yale, Hamilton Eye Univ. TN, and Univ Alabama Optometry), reported 94% and 92% accuracy respectively in separating glaucomatous from non-glaucoma patients using the patented icVEP protocol. An independent assessment in June 2013 in Beijing (TongRen and YouYi) report equivalent findings using icVEP: "high accuracy demonstrates the value as an aid in the diagnosis of open angle Glaucoma."
Detailed results available on request from Konan Medical.
Integrated Gaze Tracker
EvokeDx utilizes a sophisticated IR gaze tracker to assist in ensuring the patient is initially positioned correctly and remains fixated during the test. A graphical heat map provides the operator with real-time feedback.
Synchronized Data Collection
Synchronized data collection significantly enhances measurement precision. It avoids asynchronous errors that result from side-lobe leakage. (where VEP responses, other than the one of interest, can contaminate or leak into the measurement of the prior or following frequency component).
Additionally EvokeDx includes automated artifact rejection, coupled with advanced statistical algorithms to enable rigorous analysis, while providing clear and objective determinations of pass/fail test result
Advanced, multivariate analytics distill the complex VEP waveform into easy to interpret results.
Provides clear statistical assessment to determine if two response functions (e.g., OD vs. OS) differ significantly.
Magnitude-squared coherence yields a normalized measure of signal power in the response.
Statistical criteria are used with MSC to determine if each frequency response and distinct frequency mechanism in the VEP is significant.
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